Local senolysis in aged mice only partially replicates the benefits of systemic senolysis

#senescence

https://www.jci.org/articles/view/162519

''we propose that folate, and folate-mimicking peptides acting on folate receptor alpha enhance neural plasticity in a similar fashion to the OSKM (Oct4, Sox2, Klf4, and Myc) Yamanaka factors''

https://www.biorxiv.org/content/10.1101/2023.02.01.526619v2